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Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with Protease, Amylase & Lipase | Digestive Enzymes | Gluten, Dairy, and Soy Free | 90 Capsules
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Purchase options and add-ons
Brand | Vital Nutrients |
Flavor | Unflavored |
Unit Count | 90.00 Count |
Item Form | Capsule |
Item Weight | 3.2 ounces |
Item dimensions L x W x H | 4.25 x 1.75 x 1.75 inches |
Product Benefits | Supports |
Age Range (Description) | Adult |
Package Information | Bottle |
Number of Items | 1 |
About this item
- Premium Digestive Enzyme Supplement: Supports gut health, digestion, and bowel regularity with one easy-to-swallow capsule taken with meals. Helps support relief from occasional indigestion, gas, and bloating*
- Full-Strength Pancreatic Enzymes For Humans Healthy Digestion: Lactose-free pancreatin includes protease, lipase enzymes, and amylase enzymes to support digestion and nutrient absorption from protein, fats, and carbohydrates*
- Clean Formula: Free from gluten, dairy, peanut, tree nut, fish, shellfish, soy, sesame, and egg. Non-GMO. Made without artificial fillers, coatings, binders, or colors.
- Quality You Can Rely on: Vital Nutrients supplements are manufactured in our allergen-free, NSF-certified Middletown, CT facility. Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure what’s on the label matches what’s in the bottle
- Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide
Competitively priced item
Frequently bought together

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Product Description




We Make Clean Supplements That Work
![]() Pancreatic Enzymes | ![]() Vegan Pancreatic Enzymes | ![]() Pancreatin and OX Bile | ![]() Betaine HCL | ![]() GI Repair Nutrients | |
---|---|---|---|---|---|
Customer Reviews
|
4.4 out of 5 stars 2,213
|
4.3 out of 5 stars 41
|
4.5 out of 5 stars 834
|
4.5 out of 5 stars 343
|
4.4 out of 5 stars 129
|
Price
| $39.90$39.90 | $38.00$38.00 | $31.90$31.90 | $36.90$36.90 | $47.90$47.90 |
Dosage
| 2 capsules with a meal | 1 capsule with a meal | 2 capsules with a meal | 2 capsules with a meal | 3 capsules, 3 times daily |
Main Benefit
| Digestive Support | Digestive Support | Digestive Support | Digestive Support | Digestive Support |
Highlights
| Best Selling Digestive Enzyme | Vegan form enzyme blend | Ox Bile for added support | Herbal formula | Intestinal comfort & function |
Key Ingredients
| Protease, Amylase, Lipase | Protease, Amylase & Lipase | Enzyme Blend + Ox Bile Extract | Betaine, Pepsin, Gentian Root | Amino acids and botanicals |
Made in NSF-Certified Facility
| ✔ | ✔ | ✔ | ✔ | ✔ |
Clean Formula
| ✔ | ✔ | ✔ | ✔ | ✔ |
Lactose-Free
| ✔ | ✔ | ✔ | ✔ | ✔ |
Free of top 9 allergens
| ✔ | ✔ | ✔ | ✔ | ✘ |
Non-GMO
| ✔ | ✔ | ✔ | ✔ | ✔ |
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 4.25 x 1.75 x 1.75 inches; 3.2 ounces
- Date First Available : December 4, 2006
- Manufacturer : Vital Nutrients
- ASIN : B005HXOBFA
- Country of Origin : USA
- Best Sellers Rank: #8,347 in Health & Household (See Top 100 in Health & Household)
- Customer Reviews:
Compare with similar items
This Item ![]() Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with Protease, Amylase & Lipase | Digestive Enzymes | Gluten, Dairy, and Soy Free | 90 Capsules | Recommendations | |||||
Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | |
Price | $39.90$39.90 | -8% $69.69$69.69 List: $75.90 | $28.99$28.99 | $249.99$249.99 | $29.99$29.99 | -15% $16.99$16.99 List: $19.99 |
Price Per Unit | $0.44 / count | $0.39 / count | $0.16 / count | $5.00 / count | $0.25 / count | $0.07 / count |
Delivery | Get it as soon as Thursday, May 15 | Get it May 15 - 20 | Get it as soon as Thursday, May 15 | Get it as soon as Thursday, May 15 | Get it as soon as Thursday, May 15 | Get it as soon as Thursday, May 15 |
Customer Ratings | ||||||
Sold By | Pattern. | Adaptoid Procurement | PureFormulas Official Store | Diabetic Online. | Natures Craft Deals | Carlyle |
keyword type | multi-enzymes-nutritional-supplements | multi-enzymes-nutritional-supplements | multi-enzymes-nutritional-supplements | multi-enzymes-nutritional-supplements | multi-enzymes-nutritional-supplements | multi-enzymes-nutritional-supplements |
form | Capsule | Capsule | Tablet | Capsule | Capsule | Caplet |
flavor | Unflavored | — | Unflavored | Unflavored | Unflavored | Unflavored |
size | 90 Count (Pack of 1) | 180 Count (Pack of 1) | 180 Count (Pack of 1) | 50 Count (Pack of 1) | 120 Count (Pack of 1) | 250 Count (Pack of 1) |
weight | 0.2 pounds | 0.18 kilograms | 0.1 ounces | 60 grams | 0.19 pounds | 1500 milligrams |
age range | Adult | Adult | — | — | Adult | Adult |
product benefit | Supports | Supports | Digestive Health Support | Digestive Health Support | Digestive Health Support | Nutritional Supplement |
serving suggestion | 2 capsules | 2 capsules | One Tablet | — | — | One Capsule |
Videos
Important information
Safety Information
If pregnant, consult your physician before taking.
Indications
Vital Nutrients - Pancreatic Enzymes Supplement (Full Strength) - Supports Healthy Digestion of Proteins, Fats, and Carbohydrates - Suitable for Men and Women
Ingredients
Amount Per Serving: 2 capsules contain: Full Strength Pancreatin providing: 1000mg, Protease 223,000 USP units, Amylase 245,000 USP units, Lipase 35,500 USP units. Other ingredients: Gelatin Capsule, Cellulose, Calcium Carbonate, and Ascorbyl Palmitate. Lactose Free.
Directions
1 or 2 capsules after a meal, or as directed by a healthcare practitioner.
Legal Disclaimer
*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers find the pancreatic enzyme supplement effective, noting it works better than expensive prescription alternatives and helps with fat absorption. The product receives positive feedback for its quality and value, with customers appreciating it as a good Creon substitute and noting it's more affordable. While the enzyme quality is good, some customers report stomach pain and nausea, and several mention the product has a terrible smell.
AI-generated from the text of customer reviews
Customers find the pancreatic enzyme supplement effective, with some noting it works better than expensive prescription alternatives.
"It really worked! It totally solved my problem. Try this if you have diarrhea. But this was so amazing you need to read my story...." Read more
"...and even my gastro doc was surprised and impressed at the high levels in this product...." Read more
"Typically a very effective replacement for my Cre** , nearly same effective ingredient...." Read more
"For me better than creon and cheaper." Read more
Customers report positive effects on digestion, with the supplement helping with food digestion and absorption of fat-soluble nutrients. One customer mentions it eliminated their constipation and acid reflux, while another notes it's a daily staple for digestive support.
"...because it just contained what I needed, the enzymes, with no other ingredients added that I might be allergic to. Also the price was right...." Read more
"This is better than any other digestive enzyme I have tried as the quantity of the 3 enzymes in this blend is much higher than any other I've found..." Read more
"...with an exp date has been so helpful given me energy, helped with malnutrution...." Read more
"Does it help with stools? Yes. I had to stop taking them. They gave me the WORST anxiety...." Read more
Customers find the pancreatic enzyme supplement to be very affordable, particularly noting that it saves expensive Creon for meals, and one customer mentions it is more effective than Creon for 1/4th the price.
"...Also the price was right. Well, I can tell you I HIT THE JACKPOT...." Read more
"For me better than creon and cheaper." Read more
"...and they do not taste good at all but they are a lot cheaper than the prescription enzymes ." Read more
"...purchase this because you get what you pay for, and obviously your being cheap. You might dislike your gut...." Read more
Customers find these pancreatic enzymes excellent, with one customer noting their effectiveness in breaking down fats and carbs.
"...Super Enzymes has a little bit of everything, the pancreatic enzymes, some papain, some bromelain, pepsin, a little betaine, some ox bile--and that..." Read more
"They helped with breaking down fats and carbs, However they smell bad. Makes Urine smell bad. switching to another generic called Kreon...." Read more
"Easy to swallow and easy to get the three enzymes easily" Read more
"Much less difficulty processing fats and carbs. They are large so if you have a problem swallowing pills these are not for you" Read more
Customers find the pancreatic enzyme supplement to be a good Creon substitute, with one customer noting it works as a 1:1 replacement.
"Typically a very effective replacement for my Cre** , nearly same effective ingredient...." Read more
"...(1000 mg) for about 5 weeks now, and can say that for me, it is a 1:1 replacement. 2-3 of these with a meal, and 1 with a snack works just fine...." Read more
"...First time incredible naseua. Next few times my chest would burn. I’ve been scared to take it since as it always had this expired taste to it...." Read more
"...Vital Nutrients for a month or so now and it seems to be a satisfactory substitute...." Read more
Customers find these digestive enzymes to be of good quality, with one customer noting they result in solid, normal bowel movements.
"...I am still taking them. I am feeling strong and full of energy, capable of dealing with my 4 and 6 year old great grandkids...." Read more
"...I put her on Vital Nutrients and she has solid poops, has finally gained a little weight, and seems more comfortable. Truly a good product." Read more
"...the product quality looks consistent with the first bottle and of high quality. I would recommend that you give this product a try...." Read more
"...No more black, oily, smelly diarrhea. Now it is firm brown normal poop. I had given up hope of ever having regular bowels...." Read more
Customers report that the supplement has a terrible smell.
"...They were stronger bile taste and smelled stronger than usual...." Read more
"...I had two other bottles and I opened them as well and they also smelled. I carry a small bottle with these pills in it...." Read more
"...There is a terrible smell when the bottle is opened and they do not taste good at all but they are a lot cheaper than the prescription enzymes ." Read more
"...FYI, Sometimes the capsules can be stinky but take it with some juice or flavored water and you wont be able to tell...." Read more
Customers report severe stomach issues with this enzyme supplement, including nausea, diarrhea, cramps, and bloating.
"...Results were dizziness, heart palpatations, tachycardia, constant nauseau, confusion, lethargy...." Read more
"...Yes. I had to stop taking them. They gave me the WORST anxiety...." Read more
"Well, I guess it didn't agree with me at all: made me very sick (lots of unquestionable diarrhea for sure)...." Read more
"Decided to just try one, mistake.. I had terrible sharp pains, and was nauseous all day. The smell when I opened the bottle was horrible...." Read more
Reviews with images

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Top reviews from the United States
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- Reviewed in the United States on January 3, 2016Size: 90 Count (Pack of 1)Verified PurchaseIt really worked! It totally solved my problem. Try this if you have diarrhea. But this was so amazing you need to read my story. For 2 months I had been suffering from diarrhea. A copule of hours or little more after I ate, straight to the bathroom! I was diagnosed Irritable Bowel Syndrome - D. All kinds of laboratory tests were performed and everything was OK. During this time I went twice to my primary doctor, to another doctor in a city where I was visiting my daughter and to a psychologist because they said my IBS symptoms were due to stress. I was prescribed Librax to relax the nerves of my digestive system. (I hate and try to avoid taking this kind of drugs). I only ate sweet potatoes, rice, chicken breast or lean fish. Nothing helped. My diarrhea continued with more or less frequency.. So I called my primary doctor’s office to find out what to do next since nothing was working. The nurse asked him and he told her, “Go to a gastroenterologist.There is nothing else I can do for her.·" I was really scared. Since the first appointment I could get was one month away, I had lost 15 pounds already and was feeling weak and lethargic, I decided to do some research in the Internet to try to find some help. I read in medical website that sometimes diarrhea is caused by a lack of pancreatic enzymes because, with time, the pancreas stops producing them or does not produce enough to do their job digesting proteins, carbohydrates and fats, so the food passes too fast through the digestive system and the result is diarrhea and not absorbing the nutrients in the food. So I went to the drugstore to buy an enzyme supplement, but they would not sell them without a prescription. Back to the internet. When I searched for pancreatic enzymes VITAL Nutrients Pancreatic Enzymes Supplement turned up together with other brands. I chose it because it just contained what I needed, the enzymes, with no other ingredients added that I might be allergic to. Also the price was right. Well, I can tell you I HIT THE JACKPOT. In one day my condition improved by less frequent movements and continued to improve every day after that until in less than a week I was back to normal again. I am still taking them. I am feeling strong and full of energy, capable of dealing with my 4 and 6 year old great grandkids. I am on vacation now, but soon as I return home I am going to a new primary doctor (I fired my old one) and tell her the whole story. I will keep you posted as to what she says.
- Reviewed in the United States on May 9, 2025Size: 90 Count (Pack of 1)Verified PurchaseThe pancreas is an important organ in the body. If it doesn't break down the proteins properly. Your body can suffer from extreme pain every time you eat protein. And that's what was happening for me. It's a great product
- Reviewed in the United States on August 22, 2024Size: 90 Count (Pack of 1)Verified PurchaseTypically a very effective replacement for my Cre** , nearly same effective ingredient. However, one product bottle had no expiration date on it like the other ones we've purchased. They made me very sick for weeks of taking them. Results were dizziness, heart palpatations, tachycardia, constant nauseau, confusion, lethargy. They were stronger bile taste and smelled stronger than usual. The new product we bought again after this bottle has the date on it and tastes and smells better. I'm feeling better with the new bottle. Sending the old one to FDA for analysis. This review has nothing to do with shipping, packaging , or with supplier, it its about the product inside and it's effective ingredients as well as it's effectiveness with my severe Enzymatic Pacreatic Insufficiency treatment. Typically, product with an exp date has been so helpful given me energy, helped with malnutrution. I have recent bloodwork that shows the effectiveness, but also the effects of the last batch that made me sick.
4.0 out of 5 starsTypically a very effective replacement for my Cre** , nearly same effective ingredient. However, one product bottle had no expiration date on it like the other ones we've purchased. They made me very sick for weeks of taking them. Results were dizziness, heart palpatations, tachycardia, constant nauseau, confusion, lethargy. They were stronger bile taste and smelled stronger than usual. The new product we bought again after this bottle has the date on it and tastes and smells better. I'm feeling better with the new bottle. Sending the old one to FDA for analysis. This review has nothing to do with shipping, packaging , or with supplier, it its about the product inside and it's effective ingredients as well as it's effectiveness with my severe Enzymatic Pacreatic Insufficiency treatment. Typically, product with an exp date has been so helpful given me energy, helped with malnutrution. I have recent bloodwork that shows the effectiveness, but also the effects of the last batch that made me sick.Last pills made me very sick, but had no expiration date like other bottles
Reviewed in the United States on August 22, 2024
Images in this review
- Reviewed in the United States on November 4, 2024Size: 90 Count (Pack of 1)Verified PurchaseThis is better than any other digestive enzyme I have tried as the quantity of the 3 enzymes in this blend is much higher than any other I've found over the counter. I was having to take 3 or 4 times the recommended amount of Silver Fern or Pure Encapsulations, which are both great products and used to work for me ... until I needed something more. I'm currently undergoing testing for pancreatic enzyme insufficiently, and even my gastro doc was surprised and impressed at the high levels in this product. This has made a world of difference in my digestive system and won't go without it!
- Reviewed in the United States on March 12, 2025Size: 180 Count (Pack of 1)Verified PurchaseMuch more reasonable cost wise then medical prescriptions with same quantities.
- Reviewed in the United States on March 4, 2025Size: 90 Count (Pack of 1)Verified PurchaseFor me better than creon and cheaper.
- Reviewed in the United States on September 10, 2024Size: 90 Count (Pack of 1)Verified PurchaseDoes it help with stools? Yes.
I had to stop taking them. They gave me the WORST anxiety. I felt like I was going to have a heart attack and my brain was constantly in “doomsday” moments. I took them for 6 days and I had to stop. BEWARE
- Reviewed in the United States on April 15, 2025Size: 180 Count (Pack of 1)Verified PurchaseMy most recent purchase, the capsules are different from before. The capsule is larger and inside the capsule was white and is now beige. The ingredients have also changed from Vegetarian Capsule (Cellulose) to Gelatin Capsule. Does this mean they’re no longer vegetarian? I’m not sure yet if this will make any difference in results. The bottle for 180 capsules is also larger to accommodate the larger capsules.
5.0 out of 5 starsMy most recent purchase, the capsules are different from before. The capsule is larger and inside the capsule was white and is now beige. The ingredients have also changed from Vegetarian Capsule (Cellulose) to Gelatin Capsule. Does this mean they’re no longer vegetarian? I’m not sure yet if this will make any difference in results. The bottle for 180 capsules is also larger to accommodate the larger capsules.Change in product
Reviewed in the United States on April 15, 2025
Images in this review
Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.
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Product Summary: Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with Protease, Amylase & Lipase | Digestive Enzymes | Gluten, Dairy, and Soy Free | 90 Capsules
From Vital Nutrients
Price
One-time purchase: $39.90 ( $0.44 / count)
Subscribe & Save price (No fees, Cancel anytime): $37.90 ( $0.42 / Count) 5% Savings
List Price: $39.90
Additional savings available through Subscribe & Save (No fees, Cancel anytime)
About this Item
- Premium Digestive Enzyme Supplement: Supports gut health, digestion, and bowel regularity with one easy-to-swallow capsule taken with meals. Helps support relief from occasional indigestion, gas, and bloating*
- Full-Strength Pancreatic Enzymes For Humans Healthy Digestion: Lactose-free pancreatin includes protease, lipase enzymes, and amylase enzymes to support digestion and nutrient absorption from protein, fats, and carbohydrates*
- Clean Formula: Free from gluten, dairy, peanut, tree nut, fish, shellfish, soy, sesame, and egg. Non-GMO. Made without artificial fillers, coatings, binders, or colors.
- Quality You Can Rely on: Vital Nutrients supplements are manufactured in our allergen-free, NSF-certified Middletown, CT facility. Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure what’s on the label matches what’s in the bottle
- Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide
Product Description
Important Information
Safety Information
If pregnant, consult your physician before taking.
Indications
Vital Nutrients - Pancreatic Enzymes Supplement (Full Strength) - Supports Healthy Digestion of Proteins, Fats, and Carbohydrates - Suitable for Men and Women
Ingredients
Amount Per Serving: 2 capsules contain: Full Strength Pancreatin providing: 1000mg, Protease 223,000 USP units, Amylase 245,000 USP units, Lipase 35,500 USP units. Other ingredients: Gelatin Capsule, Cellulose, Calcium Carbonate, and Ascorbyl Palmitate. Lactose Free.
Directions
1 or 2 capsules after a meal, or as directed by a healthcare practitioner.
Legal Disclaimer
*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product.
Legal Disclaimer
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
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